勝一化工股份有限公司
Clone/ABfeature:
(#16R6)Antigen:
MouseR‑Spondin4Stability:
Lyophilizedsamplesarestablefor2yearsfromdateofreceiptwhenstoredat-70°C.Reconstitutedantibodycanbealiquotedandstoredfrozenat< -20 °C for at least for six months without detectable loss of activity.Reconstitution:
Reconstitutetheantibodywith500µlsterilePBSandthefinalconcentrationis200µg/ml.Description:
TheR-Spondin(Rspo)proteinsbelongtotheRspofamilyofWntmodulators.Currently,thefamilyconsistsoffourstructurallyrelatedsecretedligands(Rspo1-4),allcontainingfurin-likeandthrombospondinstructuraldomains.TheRspoproteinscaninteractwiththeFrizzled/LRP6receptorcomplexinamannerthatcausesthestabilizationandresultingaccumulationoftheintracellularsignalingprotein,β-catenin.Thisactivityeffectivelyactivatesandincreasesthesubsequentnuclearsignalingofβ-catenin.R-SpondincanalsobindtothepreviouslydiscoveredG-proteincoupledreceptors,LGR-4andLGR-5.Rspo/β-cateninsignalingcanactasaninducerofthetransformedphenotype,andcanalsoregulatetheproliferationanddifferentiationofcertainstemcellpopulations. RecombinanthumanR-Spondin-3isa26.9kDaproteinconsistingof240aminoacidresidues. Duetoglycosylation,R-Spondin-3migratesatanapparentmolecularweightofapproximately37.0kDabySDSPAGEanalysisunderreducingconditions.免责声明 本文仅代表作者个人观点,与本网无关。其创作性以及文中陈述文字和内容未经本站证实,对本文以及其中全部或者部分内容、文字的真实性、完整性、及时性本站不做任何保证或承诺,请读者仅作参考,并请自行核实相关内容。
版权声明 未经蚂蚁淘授权不得转载、摘编或利用其他方式使用上述作品。已经经本网授权使用作品的,应该授权范围内使用,并注明“来源:蚂蚁淘”。违反上述声明者,本网将追究其相关法律责任。
发布于 : 2021-08-19
阅读(186)
▍
相关分类
▍
相关文章
InVivoMab antimouse CTLA4 (CD152) 价格
企业风采,淄博鑫兴辉新材料科技有限公司 LookChem
Antimouse IgG Antibody | Abbiotec
NSKbearing|FAGbearing|NTNbearing|INAbearing| – …
碧云天(beyotime)一抗价格采购供应商信息
金典原阿尔发 塑料平皿培养皿35*15mm 一次性医用耗材实验器皿_价格...
小鼠基质细胞衍生因子1a(SDF1a/CXCL12)ELISA试剂盒 WSJH30336A...
h5禽流感病毒_h5禽流感病毒【价格,厂家,图片,批发,采购】
注射破伤风抗毒素(一种动物血清蛋白)是抗原还是抗体?
胶原酶II(CollagenaseII)ELISA检测试剂盒_价格厂家供应商_上海晶...
勝一化工股份有限公司
无菌实验室设计方案和规划是怎样的呢