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Tocris/8-Bromo-cGMP, sodium salt/1089/10/10 mg

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Tocris/8-Bromo-cGMP, sodium salt/1089/10/10 mg

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Tocris

货号 /

1089/10

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4000-520-616

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Description:cGMPanalog;activatesPKG

ChemicalName:8-Bromoguanosinecyclic3',5'-monophosphatesodiumsalt

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

MembranepermeablecGMPanalogthatactivatesproteinkinaseG(PKG).4.3-foldmorepotentthancGMPinactivatingPKG1αandpromotesrelaxationoftrachealandvascularsmoothmuscletissueinvitro.

TechnicalData

M.Wt	446.09
Formula	C₁₀H₁₀BrN₅NaO₇P
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	51116-01-9
PubChemID	23702959
InChIKey	ZJRFCXHKYQVNFK-YEOHUATISA-M
Smiles	[Na+].[H][C@@]12COP([O-])(=O)O[C@@]1([H])[C@@H](O)[C@@H](O2)N1C(Br)=NC2=C1NC(N)=NC2=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	44.61	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight446.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.24mL	11.21mL	22.42mL
5mM	0.45mL	2.24mL	4.48mL
10mM	0.22mL	1.12mL	2.24mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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