
Overview:
LOXL4orlysyloxidase-like4isamemberofthelysyloxidasefamilyofamineoxidases.LOXL4catalyzesthefinalenzymaticsteprequiredforthelysine-derivedcrosslinksessentialfortheformationofcollagenfibrilsandinsolubleelasticfiberswithintheextracellularmatrix(1).LOXL4canalsocontributetodevelopmentalregulation,senescence,tumorsuppression,cellgrowthcontrol,andchemotaxis.LOXL4ishighlyexpressedinskeletalmuscle,testis,andpancreas(2).
GeneAliases:
LOXC,FLJ21889
GenbankNumber:
BC013153
References:
1.Asuncion,L.et.al:Anovelhumanlysyloxidase-likegene(LOXL4)onchromosome10q24hasanalteredscavengerreceptorcysteinerichdomain.MatrixBiol.20:487-491,2001.2.Maki,J.M.et.al:Cloningandcharacterizationofafifthhumanlysyloxidaseisoenzyme:thethirdmemberofthelysyloxidase-relatedsubfamilywithfourscavengerreceptorcysteine-richdomains.MatrixBiol.20:493-496,2001.
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算上其他生物24种
大概是记不太清了

