
Overview:
1-phosphatidylinositol4,5-bisphosphatephosphodiester-asebeta-1(PLCB1)isoneofthebestcharacterizedisoenzymesintheinositidespecificphospholipaseC(PI-PLC)family.ResponsIBLeforthehydrolysisofthephosphatidilinool-4,5-bisphophate(PIP2),generatingthesecondmessengersinositol-1,4,5-triphosphateanddi-acylglycerol.Itisakeymoleculefornuclearinositidesignaling,whereitplaysaroleincellcycleprogression,proliferationanddifferentiation.
GeneAliases:
EIEE12;PI-PLC;PLC-154;PLC-I;PLC154;PLCB1A;PLCB1B
GenbankNumber:
NM_015192
References:
1.FaenzaI,etal:AroleforPLCbeta1inmyotonicdystrophiestype1and2.FasebJ.26:3042–3048,2012.2.FaenzaI,etal:NuclearinositidespecificphospholipaseCsignalling-interactionsandactivity.FEBSJ.280(24):6311-21,2013.
ebiomall.com






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算上其他生物24种
大概是记不太清了

