
Overview:
HSP70isamemberoftheheatshockproteinfamilyandissynthesizedbycellsofmanyorganismsinresponsetostress(1).HSP70isfoundmostlybutnotexclusivelyinthenucleusofunstressedcells.Forseveralhoursafterashortheatshock,however,itisstronglyconcentratedinnucleoli(2).Nucleoliaretransientlydamagedbysuchaheatshock:theirmorphologychangesandassemblyandexportofribosomesisblockedforseveralhours.HSP70helpstostABIlizethemorphologicalchangesofthenucleoli.
GeneAliases:
HSPA1A,HSP72,HSPA1,HSPA1B,HSP70-1
GenbankNumber:
NM_005345
References:
1.Moran,LA.etal:Themajorheat-shockprotein(hsp70)genefamily:relatedsequencesinmouse,Drosophila,andyeast.CanJBiochemCellBiol.1983Jun;61(6):488-99.2.Pelham,HR:Hsp70acceleratestherecoveryofnucleolarmorphologyafterheatshock.EMBOJ.1984Dec20;3(13):3095-100.
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算上其他生物24种
大概是记不太清了

