BiologicalActivity
Inhibitorofhumanandbovineactin-relatedprotein2/3(Arp2/3)complex.Inhibitsactinpolymerization(IC50=11μM).DoesnotinhibitbuddingorfissionyeastArp2/3complexes.
TechnicalData
| M.Wt | 394.28 |
| Formula | C17H16BrNO3S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 388592-44-7 |
| PubChemID | 3574452 |
| InChIKey | MVWNPZYLNLATCH-UHFFFAOYSA-N |
| Smiles | O=C1N(C3=CC=C(OC)C=C3OC)C(C2=CC=CC(Br)=C2)SC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 39.43 | 100 | |
| ethanol | 3.94 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight394.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.54mL | 12.68mL | 25.36mL |
| 5mM | 0.51mL | 2.54mL | 5.07mL |
| 10mM | 0.25mL | 1.27mL | 2.54mL |
| 50mM | 0.05mL | 0.25mL | 0.51mL |
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