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Description:Disruptsactinfilamentfunction
AlternativeNames:ZygosporinA
ChemicalName:(7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentdisruptorofactinfilamentfunction.AlterstightjunctionpermeABIlity.UnlikecytochalasinB(Cat.No.5474),doesnotinhibitmonosaccharidetransportacrosstheplasmamembrane.
TechnicalData
M.Wt | 507.63 |
Formula | C30H37NO6 |
Storage | Desiccateat-20°C |
Purity | ≥95%(HPLC) |
CASNumber | 22144-77-0 |
PubChemID | 98137101 |
InChIKey | SDZRWUKZFQQKKV-HYKYWQBKSA-N |
Smiles | C=C([C@H]4C)[C@@H](O)[C@]([C@@]1([C@H](OC(C)=O)/C=C/[C@@](O)3C)[C@]4([H])[C@@H](CC2=CC=CC=C2)N[C@]1=O)([H])/C=C/C[C@H](C)C3=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 25.38 | 50 | |
ethanol | 5.08 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight507.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.97mL | 9.85mL | 19.7mL |
5mM | 0.39mL | 1.97mL | 3.94mL |
10mM | 0.2mL | 0.98mL | 1.97mL |
50mM | 0.04mL | 0.2mL | 0.39mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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