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Description:Inhibitorofactinassemblyandpolymerization
ChemicalName:4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxABIcyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
ReversIBLeinhibitorofactinassembly;blocksactinadeninenucleotideexchange.Complexeswithactininvitroandinteractswithactinmonomersonly,unlikecytochalasins.PreventsactinrepolymerizationintofilamentsanddisruptstheactinCytoskeleton.
TechnicalData
| M.Wt | 421.55 |
| Formula | C22H31NO5S |
| Storage | Storeat-20°C |
| CASNumber | 76343-93-6 |
| PubChemID | 445420 |
| InChIKey | DDVBPZROPPMBLW-IZGXTMSKSA-N |
| Smiles | C[C@@H](CC[C@]2([H])C[C@@](C[C@](O)([C@]3([H])CSC(N3)=O)O2)([H])O1)C=C/C=C/CC/C(C)=CC1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.22 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight421.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.37mL | 11.86mL | 23.72mL |
| 5mM | 0.47mL | 2.37mL | 4.74mL |
| 10mM | 0.24mL | 1.19mL | 2.37mL |
| 50mM | 0.05mL | 0.24mL | 0.47mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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