BiologicalActivity
InhibitsneuralWiskott-Aldrichsyndromeprotein(N-WASP)bystABIlizingtheautoinhibitedstateoftheprotein.Blocksphosphatidylinositol4,5-bisphosphate(PIP2)-stimulatedactinassembly(IC50~2μM)butdoesnotdirectlyinhibitactinpolymerization.
TechnicalData
| M.Wt | 1784.13 |
| Formula | C96H122N18O16 |
| Sequence | KFPFFPQKFPFFPQ (Modifications:Phe-2=D-Phe,Pro-3=D-Pro,Phe-4=D-Phe,Pro-6=D-Pro,Cyclized) |
| Storage | Desiccateat-20°C |
| CASNumber | 380488-27-7 |
| PubChemID | 44405676 |
| InChIKey | PHTIQAVQWWOKNF-RNEDXEELSA-N |
| Smiles | NCCCC[C@@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CC2=CC=CC=C2)NC1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto2mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1784.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.56mL | 2.8mL | 5.6mL |
| 5mM | 0.11mL | 0.56mL | 1.12mL |
| 10mM | 0.06mL | 0.28mL | 0.56mL |
| 50mM | 0.01mL | 0.06mL | 0.11mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。