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Description:FH2domaininhibitor;preventsactinnucleation
ChemicalName:1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inhibitorofforminhomology2(FH2)domains.Preventsformin-mediatedactinnucleationandbarbedendelongation.Disruptsformin-dependentactincytoskeletalstructuresinfissionyeastandmammalianNIH3T3fibroblasts.
TechnicalData
M.Wt | 377.21 |
Formula | C15H9BrN2O3S |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 340316-62-3 |
PubChemID | 2258538 |
InChIKey | MVFJHEQDISFYIS-XYOKQWHBSA-N |
Smiles | O=C(/C(C(N2)=O)=C/C1=CC=CO1)N(C3=CC=CC(Br)=C3)C2=S |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 37.72 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight377.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.65mL | 13.26mL | 26.51mL |
5mM | 0.53mL | 2.65mL | 5.3mL |
10mM | 0.27mL | 1.33mL | 2.65mL |
50mM | 0.05mL | 0.27mL | 0.53mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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