BiologicalActivity
Inhibitorofforminhomology2(FH2)domains.Preventsformin-mediatedactinnucleationandbarbedendelongation.Disruptsformin-dependentactincytoskeletalstructuresinfissionyeastandmammalianNIH3T3fibroblasts.
TechnicalData
| M.Wt | 377.21 |
| Formula | C15H9BrN2O3S |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 340316-62-3 |
| PubChemID | 2258538 |
| InChIKey | MVFJHEQDISFYIS-XYOKQWHBSA-N |
| Smiles | O=C(/C(C(N2)=O)=C/C1=CC=CO1)N(C3=CC=CC(Br)=C3)C2=S |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.72 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight377.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.65mL | 13.26mL | 26.51mL |
| 5mM | 0.53mL | 2.65mL | 5.3mL |
| 10mM | 0.27mL | 1.33mL | 2.65mL |
| 50mM | 0.05mL | 0.27mL | 0.53mL |
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