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Tocris/Actinomycin D/1229/10/10 mg

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Tocris

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1229/10

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4000-520-616

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Description:InhibitsRNApolymerase

ChemicalName:2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Anti-neoplasticantibiotic.InhibitsRNApolymeraseandisapotentinducerofapoptosis.

TechnicalData

M.Wt	1255.43
Formula	C₆₂H₈₆N₁₂O₁₆
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	50-76-0
PubChemID	2019
InChIKey	RJURFGZVJUQBHK-UHFFFAOYSA-N
Smiles	CC(C)C1NC(=O)C(NC(=O)C2=CC=C(C)C3=C2N=C2C(O3)=C(C)C(=O)C(N)=C2C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	62.77	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1255.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.8mL	3.98mL	7.97mL
5mM	0.16mL	0.8mL	1.59mL
10mM	0.08mL	0.4mL	0.8mL
50mM	0.02mL	0.08mL	0.16mL

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BiologicalActivity

TechnicalData

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