BiologicalActivity
Potentandselectivetankyrase(TNKS)inhibitor(IC50valuesare6and72nMforTNKS1andTNKS2respectively).HasnosignificanteffectonPARP-1orPARP-2(IC50>19μM).InhibitsWNT/β-cateninsignaling-dependentSuper-TopFlash(STF)luciferaseactivity.
TechnicalData
| M.Wt | 264.32 |
| Formula | C18H16O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 92831-11-3 |
| PubChemID | 2802462 |
| InChIKey | PYTOHIUBXSJKQH-UHFFFAOYSA-N |
| Smiles | O=C2C1=CC=CC=C1OC(C3=CC=C(C(C)C)C=C3)=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.43 | 100 | |
| ethanol | 26.43 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight264.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.78mL | 18.92mL | 37.83mL |
| 5mM | 0.76mL | 3.78mL | 7.57mL |
| 10mM | 0.38mL | 1.89mL | 3.78mL |
| 50mM | 0.08mL | 0.38mL | 0.76mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。