品牌试剂实验Tocris代理 Tocris配体,Tocris/MN 64/5084/50/50 mg,DNA聚合酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/MN 64/5084/50/50 mg

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Tocris

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5084/50

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4000-520-616

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Description:Potentandselectivetankyraseinhibitor

ChemicalName:2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivetankyrase(TNKS)inhibitor(IC₅₀valuesare6and72nMforTNKS1andTNKS2respectively).HasnosignificanteffectonPARP-1orPARP-2(IC₅₀>19μM).InhibitsWNT/β-cateninsignaling-dependentSuper-TopFlash(STF)luciferaseactivity.

TechnicalData

M.Wt	264.32
Formula	C₁₈H₁₆O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	92831-11-3
PubChemID	2802462
InChIKey	PYTOHIUBXSJKQH-UHFFFAOYSA-N
Smiles	O=C2C1=CC=CC=C1OC(C3=CC=C(C(C)C)C=C3)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	26.43	100
	ethanol	26.43	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight264.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.78mL	18.92mL	37.83mL
5mM	0.76mL	3.78mL	7.57mL
10mM	0.38mL	1.89mL	3.78mL
50mM	0.08mL	0.38mL	0.76mL

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