BiologicalActivity
Anti-inflammatoryagent.Inhibitorofpoly(ADP-ribose)polymerase(PARP-1)enzymes.NAD+precursor.Promotesdifferentiationofmesenchymalstemcellstoinsulinproducingcellswhenusedincombinationwithgrowthfactorsandhighglucoseconcentration.
CompoundLibraries
NicotinamideisalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 122.12 |
| Formula | C6H6N2O |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 98-92-0 |
| PubChemID | 936 |
| InChIKey | DFPAKSUCGFBDDF-UHFFFAOYSA-N |
| Smiles | O=C(C1=CC=CN=C1)N |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 12.21 | 100 | |
| ethanol | 12.21 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight122.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 8.19mL | 40.94mL | 81.89mL |
| 5mM | 1.64mL | 8.19mL | 16.38mL |
| 10mM | 0.82mL | 4.09mL | 8.19mL |
| 50mM | 0.16mL | 0.82mL | 1.64mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
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