中国Tocris官网，Tocris Bioscience价格更新品牌试剂实验代理,Tocris/AM-TS23/5211/50/50 mg,DNA聚合酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/AM-TS23/5211/50/50 mg

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Tocris

货号 /

5211/50

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4000-520-616

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Description:DNApolymeraseλandβinhibitor

ChemicalName:(5Z)-5-[[(4-[(2-Methylphenyl)thio]-3-nitrophenyl]methylene]-2-thioxo-4-thiazolidinone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

DNApolymeraseλandβinhibitor(IC₅₀valuesare3.9and18.2μM,respectively).Sensitizeshumancolorectalcancercellstohydrogenperoxideandtemozolomide(Cat.No.2706)invitro.

TechnicalData

M.Wt	388.48
Formula	C₁₇H₁₂N₂O₃S₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1489285-17-7
PubChemID	72164414
InChIKey	SHKDXDWJERWCHI-DHDCSXOGSA-N
Smiles	O=C(/C(S2)=C/C1=CC=C(SC3=CC=CC=C3C)C([N+]([O-])=O)=C1)NC2=S

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	38.85	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.87mL	25.74mL
5mM	0.51mL	2.57mL	5.15mL
10mM	0.26mL	1.29mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

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BiologicalActivity

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