Tocris抗体品牌 Tocris GPCR ligands,Tocris/Heclin/5433/50/50 mg,连接酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Heclin/5433/50/50 mg

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Tocris

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5433/50

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4000-520-616

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Description:HECTE3ubiquitinligaseinhibitor

ChemicalName:N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HECTE3ubiquitinligaseinhibitor;inhibitsNedd4,Smurf2andWWP1(IC₅₀valuesare6.3,6.8and6.9μMrespectively).SelectiveforHECT-mediatedoverRING-mediatedubiquitination.

CompoundLibraries

HeclinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	283.32
Formula	C₁₇H₁₇NO₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	890605-54-6
PubChemID	7464118
InChIKey	SPTWXRJNCFIDRQ-ZHACJKMWSA-N
Smiles	CC(C1=CC=C(NC(/C=C/C2=CC=C(CC)O2)=O)C=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	28.33	100
	ethanol	14.17	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight283.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.53mL	17.65mL	35.3mL
5mM	0.71mL	3.53mL	7.06mL
10mM	0.35mL	1.76mL	3.53mL
50mM	0.07mL	0.35mL	0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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