Tocris公司代理生物计划 Tocris Bioscience美元价/进货价,Tocris/CID 2011756/4644/50/50 mg,其它酶,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/CID 2011756/4644/50/50 mg

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Tocris

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4644/50

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4000-520-616

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Description:PanproteinkinaseD(PKD)inhibitor;cellpermeable

ChemicalName:5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ProteinkinaseD(PKD)inhibitor(IC₅₀valuesare0.6,0.7and3.2μMforPKD2,PKD3andPKD1respectively).Cellpermeable(EC₅₀=10μMforPKD1inhibition).ATP-competitive.

CompoundLibraries

CID2011756isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	396.87
Formula	C₂₂H₂₁ClN₂O₃
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	638156-11-3
PubChemID	2011756
InChIKey	XQJWTJLJEYIUDZ-UHFFFAOYSA-N
Smiles	O=C(NC3=CC=C(CN4CCOCC4)C=C3)C1=CC=C(C2=CC=CC(Cl)=C2)O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	19.84	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight396.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.52mL	12.6mL	25.2mL
5mM	0.5mL	2.52mL	5.04mL
10mM	0.25mL	1.26mL	2.52mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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