Tocris中国采购 Tocris离子通道调控剂,Tocris/<em>N</em>-Nonyldeoxynojirimycin/3691/10/10 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/<em>N</em>-Nonyldeoxynojirimycin/3691/10/10 mg

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Tocris/N-Nonyldeoxynojirimycin/3691/10/10 mg

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Tocris

货号 /

3691/10

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4000-520-616

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Description:Glucosidaseinhibitor

AlternativeNames:NN-DNJ

ChemicalName:(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Glucosidaseinhibitor(IC₅₀valuesare0.42and8.4μMforacidα-glucosidaseandα-1,6-glucosidaserespectively).Inhibitsliverglycogenbreakdowninvivo.Alsoactsasachemicalchaperone;chaperonesβ-Glufoldingatneutralp.H.allowingthestABIlizedenzymetotransitfromtheendoplasmicreticulumtothegolgi,enablingpropertraffickingtothelysosome.

TechnicalData

M.Wt	289.41
Formula	C₁₅H₃₁NO₄
Storage	Storeat-20°C
CASNumber	81117-35-3
PubChemID	501640
InChIKey	FTSCEGKYKXESFF-LXTVHRRPSA-N
Smiles	O[C@H]1[C@H](O)[C@@H](CO)N(CCCCCCCCC)C[C@@H]1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	28.94	100
	ethanol	28.94	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight289.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.46mL	17.28mL	34.55mL
5mM	0.69mL	3.46mL	6.91mL
10mM	0.35mL	1.73mL	3.46mL
50mM	0.07mL	0.35mL	0.69mL

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