Tocris试剂采购 Tocris Bioscience代理，产品目录,Tocris/RBC8/5411/50/50 mg,其它酶,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/RBC8/5411/50/50 mg

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Tocris

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5411/50

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4000-520-616

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Description:RalAandRalBGTPaseinhibitor

ChemicalName:6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)pyrano[2,3-c]pyrazole-5-carbonitrile

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RalAandRalBGTPaseinhibitor(EC₅₀~3.5μM).InhibitsthebindingofRaltoRaLBP1.ExhibitsnodetectableinhibitionofRasorRhoAactivity.Suppressesgrowthofxenografttumorsinmice.Cellpermeable.

CompoundLibraries

RBC8isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	424.45
Formula	C₂₅H₂₀N₄O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	361185-42-4
PubChemID	6626226
InChIKey	CLMQBVUFKIKYLU-UHFFFAOYSA-N
Smiles	NC1=C(C#N)C(C5=C(OC)C=CC(OC)=C5)C(C(C3=CC=C(C=CC=C4)C4=C3)=NN2)=C2O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	42.44	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight424.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.36mL	11.78mL	23.56mL
5mM	0.47mL	2.36mL	4.71mL
10mM	0.24mL	1.18mL	2.36mL
50mM	0.05mL	0.24mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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