Tocris试剂采购 Tocris Bioscience抗体品牌,Tocris/TC-E 5002/5089/50/50 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/TC-E 5002/5089/50/50 mg

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Tocris

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5089/50

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4000-520-616

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Description:SelectiveKDM2/7inhibitor

ChemicalName:N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivehistonedemethylaseKDM2/7subfamilyinhibitor(IC₅₀valuesare0.2,1.2,6.8,55,83,>100and>120μMforKDM7A,KDM7B,KDM2A,KDM5A,KDM4C,KDM6AandKDM4Arespectively).InhibitsgrowthofHeLaandKYSE-150cancercellsinvitro.

CompoundLibraries

TC-E5002isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	285.38
Formula	C₁₅H₂₇NO₄
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1453071-47-0
PubChemID	71735843
InChIKey	NEHSERYKENINRH-UHFFFAOYSA-N
Smiles	O=C(N(CCC(O)=O)O)CCCCCCCCC1CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.NaOH	28.54	100
	DMSO	28.54	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight285.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.5mL	17.52mL	35.04mL
5mM	0.7mL	3.5mL	7.01mL
10mM	0.35mL	1.75mL	3.5mL
50mM	0.07mL	0.35mL	0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

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PreparingStockSolutions

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