Tocris产品促销 Tocris Bioscience美元价/进货价,Tocris/CVT 313/6174/50/50 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/CVT 313/6174/50/50 mg

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Tocris

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6174/50

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4000-520-616

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Description:cdk2inhibitor

ChemicalName:2,2'-[[6-[[(4-Methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis[ethanol]

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

cdk2inhibitor(IC₅₀=0.5μM).Exhibits>8-foldselectivityforCDK2overCDK1andCDK4(IC₅₀valuesare4.2and215μM,respectively).Inhibitsproliferationratneonatalaorticsmoothmusclecellsandarangeoftumorcellslinesinvitro.Inhibitsrestenosisinaratcarotidarteryinjurymodel.

TechnicalData

M.Wt	400.47
Formula	C₂₀H₂₈N₆O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	199986-75-9
PubChemID	6918386
InChIKey	NQVIIUBWMBHLOZ-UHFFFAOYSA-N
Smiles	COC1=CC=C(C=C1)CNC2=NC(N(CCO)CCO)=NC3=C2N=CN3C(C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	40.05	100
	ethanol	40.05	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight400.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.5mL	12.49mL	24.97mL
5mM	0.5mL	2.5mL	4.99mL
10mM	0.25mL	1.25mL	2.5mL
50mM	0.05mL	0.25mL	0.5mL

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