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Deubiquitinatingenzymes(DUBs)areproteasesthatpossestheABIlitytocleaveubiquitinchainsortheisopeptidebondthatconjugatesubiquitinwithasubstrate.Humancellshaveapproximately100DUBsthatplayimportantrolesinregulatingvariouscellularevents.UCHL1isoneofthefourmembersoftheubiquitinC-terminalhydrolase(UCH)family.Itisthoughttobemainlyinvolvedincleavingproubiquitinproteinsintomonomericubiquitin.
AdditionalInformation
| ProductName: | UCHL1 |
|---|---|
| AlsoKnownAs: | PARK5;PGP95;PGP9.5;Uch-L1;PGP9.5 |
| CatalogNo.: | H1101 |
| Size: | 100µg |
| MolecularWeight: | 24.8kDa |
| Species: | Human |
| Source: | Bacterialrecombinant |
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
| Concentration: | Seetubelabel |
| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
| PDFDataSheet: | PDFDatasheet,MSDS |
| NCBIRefSeq: | NM_004181 |
| Image(s): | N/A |
| ShippingMethod: | Dryiceshipping |
| References: | 1.PickartCM,etal.(1985)JBiolChem260(13),7903–7910. 2.WilkinsonKD(1997)FASEBJ11(14),1245–1256.3.LarsenCN,etal.(1998)Biochemistry37(10),3358–3368. 4.Reyes-TurcuFE,etal.(2009)AnnuRevBiochem78,363–397. |

