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Deubiquitinatingenzymes(DUBs)areproteasesthatpossestheABIlitytocleaveubiquitinchainsortheisopeptidebondthatconjugatesubiquitinwithasubstrate.Humancellshaveapproximately100DUBsthatplayimportantrolesinregulatingvariouscellularevents.UCHL1isoneofthefourmembersoftheubiquitinC-terminalhydrolase(UCH)family.Itisthoughttobemainlyinvolvedincleavingproubiquitinproteinsintomonomericubiquitin.
AdditionalInformation
ProductName: | GST-UCHL1 |
---|---|
AlsoKnownAs: | PARK5;PGP95;PGP9.5;Uch-L1;PGP9.5 |
CatalogNo.: | H1111 |
Size: | 100µg |
MolecularWeight: | 24.8kDa |
Species: | Human |
Source: | Bacterialrecombinant |
Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
Concentration: | Seetubelabel |
QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
PDFDataSheet: | PDFDatasheet,MSDS |
NCBIRefSeq: | NM_004181 |
Image(s): | N/A |
ShippingMethod: | Dryiceshipping |
References: | 1.PickartCM,etal.(1985)JBiolChem260(13),7903–7910. 2.WilkinsonKD(1997)FASEBJ11(14),1245–1256.3.LarsenCN,etal.(1998)Biochemistry37(10),3358–3368. 4.Reyes-TurcuFE,etal.(2009)AnnuRevBiochem78,363–397. |