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Deubiquitinatingenzymes(DUBs)areproteasesthatpossestheABIlitytocleaveubiquitinchainsortheisopeptidebondthatconjugatesubiquitinwithasubstrate.Humancellshaveapproximately100DUBsthatplayimportantrolesinregulatingvariouscellularevents.OTUB2isamemberoftheovariantumordomainfamily.NotmuchisknownabouttheBIOLOGicalfunctionofthisenzyme,butitmaydeubiquitinateTRAF3and-6.Thiswouldnegativelyregulatevirus-triggeredtypeIIFNinduction.
AdditionalInformation
| ProductName: | GST-OTUB2 |
|---|---|
| AlsoKnownAs: | OTB2;OTU2;C14orf137 |
| CatalogNo.: | H3111 |
| Size: | 100µg |
| MolecularWeight: | 27.2kDa |
| Species: | Human |
| Source: | Bacterialrecombinant |
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
| Concentration: | Seetubelabel |
| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
| PDFDataSheet: | PDFDatasheet,MSDS |
| NCBIRefSeq: | NM_023112 |
| Image(s): | N/A |
| ShippingMethod: | Dryiceshipping |
| References: | 1.BalakirevMY,etal.(2003)EMBORep4(5),517–522. 2.Reyes-TurcuFE,etal.(2009)AnnuRevBiochem78,363–397.3.LiS,etal.(2010)JBiolChem285(7),4291–4297. |

