进口Tocris试剂盒，血清清关 Tocris Bioscience公司代理生物计划,Tocris/AT 56/3531/10/10 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/AT 56/3531/10/10 mg

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Tocris

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3531/10

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4000-520-616

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Description:L-PGDSinhibitor

ChemicalName:4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactiveinhibitoroflipocalin-typeprostaglandinDsynthase(L-PGDS)(K_i=75μM,IC₅₀=95μM).InhibitstheproductionofPGD₂fromPGH₂invitro,withnoeffectonPGE₂orPGF_2αproduction.

TechnicalData

M.Wt	397.52
Formula	C₂₅H₂₇N₅
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	162640-98-4
PubChemID	11741525
InChIKey	LQNGMDUIRLSESZ-UHFFFAOYSA-N
Smiles	C2(C=CC=C3)=C3/C(C(C=CC=C4)=C4C=C2)=C1CCN(CCCCC5=NNN=N5)CC/1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	19.88	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight397.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.52mL	12.58mL	25.16mL
5mM	0.5mL	2.52mL	5.03mL
10mM	0.25mL	1.26mL	2.52mL
50mM	0.05mL	0.25mL	0.5mL

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