BiologicalActivity
Non-peptideangiotensin-convertingenzyme(ACE)inhibitor.Reducesbloodpressureandmyocardialhypertrophyinspontaneoushypertensiverats.
CompoundLibraries
BenazeprilhydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 460.96 |
| Formula | C24H28N2O5.HCl |
| Storage | Desiccateat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 86541-74-4 |
| PubChemID | 5362123 |
| InChIKey | VPSRQEHTHIMDQM-FKLPMGAJSA-N |
| Smiles | O=[C@@](OCC)[C@H](CCC3=CC=CC=C3)N[C@H]1CCC2=C(C=CC=C2)N(CC(O)=O)C1=O.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 46.1 | 100 | |
| ethanol | 46.1 | 100 | |
| water | 23.05 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight460.96.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.17mL | 10.85mL | 21.69mL |
| 5mM | 0.43mL | 2.17mL | 4.34mL |
| 10mM | 0.22mL | 1.08mL | 2.17mL |
| 50mM | 0.04mL | 0.22mL | 0.43mL |
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