Tocris GPCR ligands Tocris离子通道调控剂,Tocris/Cyclosporin A/1101/100/100 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Cyclosporin A/1101/100/100 mg

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Tocris

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1101/100

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4000-520-616

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Description:Calcineurininhibitor

AlternativeNames:CiclosporinA

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Immunosuppressant;inhibitsphosphataseactivityofcalcineurin(IC₅₀=5nM).AlsoinhibitsformationandopeningofthemitochondrialpermeABIlitytransitionpore(MPTP).

CompoundLibraries

CyclosporinAisalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	1202.63
Formula	C₆₂H₁₁₁N₁₁O₁₂
Storage	Desiccateat-20°C
Purity	≥99%(HPLC)
CASNumber	59865-13-3
PubChemID	2909
InChIKey	PMATZTZNYRCHOR-UHFFFAOYSA-N
Smiles	OC(C(CC=CC)C)C1C(=O)NC(C(=O)N(C)CC(N(C)C(CC(C)C)C(NC(C(=O)N(C)C(CC(C)C)C(NC(C)C(=O)NC(C)C(N(C)C(C(N(C)C(C(N(C)C(C(C)C)C(=O)N1C)=O)CC(C)C)=O)CC(C)C)=O)=O)C(C)C)=O)=O)CC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	120.26	100
	ethanol	60.13	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1202.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.83mL	4.16mL	8.32mL
5mM	0.17mL	0.83mL	1.66mL
10mM	0.08mL	0.42mL	0.83mL
50mM	0.02mL	0.08mL	0.17mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets