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Description:Insulin-regulatedaminopeptidase(IRAP)inhibitor
ChemicalName:Ethyl2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Insulin-regulatedaminopeptidase(IRAP)inhibitor(Ki=2.01μM).Improvesmemoryincontrolandmemory-deficientmicemodels.
CompoundLibraries
HFI142isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 312.32 |
Formula | C17H16N2O4 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 332164-34-8 |
PubChemID | 655457 |
InChIKey | JOPNHSIHFSZJMB-UHFFFAOYSA-N |
Smiles | OC1=CC(OC(N)=C(C(OCC)=O)C2C3=CN=CC=C3)=C2C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 31.23 | 100 | |
ethanol | 3.12 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight312.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.2mL | 16.01mL | 32.02mL |
5mM | 0.64mL | 3.2mL | 6.4mL |
10mM | 0.32mL | 1.6mL | 3.2mL |
50mM | 0.06mL | 0.32mL | 0.64mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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