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Tocris/HFI 142/5627/50/50 mg
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Tocris/HFI 142/5627/50/50 mg
品牌 / 
Tocris
货号 / 
5627/50
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4000-520-616
Description:Insulin-regulatedaminopeptidase(IRAP)inhibitor
ChemicalName:Ethyl2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Insulin-regulatedaminopeptidase(IRAP)inhibitor(Ki=2.01μM).Improvesmemoryincontrolandmemory-deficientmicemodels.

CompoundLibraries

HFI142isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt312.32
FormulaC17H16N2O4
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber332164-34-8
PubChemID655457
InChIKeyJOPNHSIHFSZJMB-UHFFFAOYSA-N
SmilesOC1=CC(OC(N)=C(C(OCC)=O)C2C3=CN=CC=C3)=C2C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.23100
ethanol3.1210mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight312.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.2mL16.01mL32.02mL
5mM0.64mL3.2mL6.4mL
10mM0.32mL1.6mL3.2mL
50mM0.06mL0.32mL0.64mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet