BiologicalActivity
Endogenousσ1receptorligandandpsychoactiveplantcompound(Ki=14.8μM).Bindingtoσ1inhibitsvoltage-gatedNa+channelsandisresponsIBLeforthebehavioraleffectsofDMT.Alsoa5-HT2Areceptoragonistandinhibitorof5-HTuptakeatplasmamembraneSEROtonintransporters(SERT)(Ki=4.0μM).
TechnicalData
| M.Wt | 188.27 |
| Formula | C12H16N2 |
| Storage | Storeat-20°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 61-50-7 |
| PubChemID | 6089 |
| InChIKey | DMULVCHRPCFFGV-UHFFFAOYSA-N |
| Smiles | CN(CCC2=CNC1=CC=CC=C12)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 0.94 | 5 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight188.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.31mL | 26.56mL | 53.12mL |
| 5mM | 1.06mL | 5.31mL | 10.62mL |
| 10mM | 0.53mL | 2.66mL | 5.31mL |
| 50mM | 0.11mL | 0.53mL | 1.06mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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