BiologicalActivity
5-HT2Aandα1adrenoceptorantagonist.EnhancesneuronaldifferentiationofmouseandhumanneuralProgenitorcells.AlsoinhibitsPERK/eIF2α-P-mediatedreductioninproteinsynthesisandrestoresmemorydeficitsinamousedementiamodel.Antidepressantandneuroprotectant.
TechnicalData
| M.Wt | 408.32 |
| Formula | C19H22ClN5O.HCl |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 25332-39-2 |
| PubChemID | 62935 |
| InChIKey | OHHDIOKRWWOXMT-UHFFFAOYSA-N |
| Smiles | ClC1=CC=CC(N2CCN(CC2)CCCN3N=C4C=CC=CN4C3=O)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.42 | 50 | |
| water | 8.17 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight408.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.45mL | 12.25mL | 24.49mL |
| 5mM | 0.49mL | 2.45mL | 4.9mL |
| 10mM | 0.24mL | 1.22mL | 2.45mL |
| 50mM | 0.05mL | 0.24mL | 0.49mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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