BiologicalActivity
HighlypotentGPR183(EBI2)agonist(EC50=140pM)andputativenaturalligandforGPR183.RegulatesmigrationofBandTcellsexpressingGPR183invivo.DesensitizesBcellsandreducestheirmovementtosplenicfollicles.
TechnicalData
| M.Wt | 418.65 |
| Formula | C27H46O3 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 64907-22-8 |
| PubChemID | 11954197 |
| InChIKey | BQMSKLCEWBSPPY-IKVTXIKFSA-N |
| Smiles | O[C@H](C1)CC[C@@]2(C)C1=C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)(O)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.19 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight418.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.39mL | 11.94mL | 23.89mL |
| 5mM | 0.48mL | 2.39mL | 4.78mL |
| 10mM | 0.24mL | 1.19mL | 2.39mL |
| 50mM | 0.05mL | 0.24mL | 0.48mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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