Description:
ChromogenixS-2222™isachromogenicsubstrateforFactorXa.Itisalsoverysensitivetotrypsin.Thesubstratehasbeenusedforthedeterminationof:
- FactorXinplasma
- FactorXainplasma
- FactorXainhibitorinplasma
- Heparininplasma
- FactorVIIIinplasma
- Coagulatingenzymefromhorseshoecrabplasma
- Trypsininduodenalfluid
Thesubstrateisalsosensitivetosubtilisin,acrosinandFactorXIIabutinsensitivetomostotherenzymestested,e.g.FactorIXa,kallikrein(glandularandplasma)andpapain-likeenzymes.
Composition:
EachvialcontainschromogenicsubstrateS-2222™25mgandmannitol120mgasabulkingagent.
Molecularwt:741.3
Formula:Bz-Ile-Glu(g-OR)-Gly-Arg-pNA·HClR=H(50%)andR=CH3(50%)
Chemicalname:N-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-Larginine-p-nitroanilinehydrochlorideanditsmethylester
FactorXaIUandEnzymeActivity:
FactorXa,whichhasamolecularweightof44KDa,istheactivatedformofFactorX(MW:59KDa).
TheInternationalUnitsofFactorXcorrespondtotheamountofFactorXcontainedin1mlofnormalplasma.Thisisabout8mg/lor0.13µmol/l.
SincethereisnoWHOstandardforFXa,onewouldassumethatifalltheFactorXinnormalplasmawasconvertedtotheactivatedform,theFactorXaconcentrationwouldbeapproximately5.7mg/l.
TheactivityofhumanFactorXaascalculatedfromthekinetictablesis1.5nkat/µgwiththechromogenicsubstrateS-2222™,and4.4µkat/µgwiththechromogenicsubstrateS-2765™.
Theactivityof1µgofFactorXaasdeterminedbyFrieberger(1)is1.9nkatchromogenicsubstrateS-2222™.
Thus,1plasmaequivalentunitofFactorXwouldcorrespondto15.2nkatchromogenicsubstrateS-2222™.
FribergerPetal.
Syntheticpeptidesubstrateassaysandfibrinolysisandtheirapplicationonautomates.In:SeminarsinThrombosisandHaemostasis,Vol.9,281-300(1983).
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请问下有无同学需要H37RA的？我是做EAE模型的，上个月购买了BDDifco公司的H37RA（货号），因为购买的时候只能整盒6支购买，但我们用不了那么多，所以想问问有无同学需要的，100mg/支，800元/支或用等价试剂交换。地址广州。有需要的请私信，谢谢！
A、Na2CO3HClH2SO4NaNO3
B、K2CO3H2SO4HNO3BaCl2
C、HClHNO3AgNO3NaCl
D、NaOHFeCl3MgCl2BaCl2
我想检测血管组织中的钙离子浓度，不知道哪个公司有试剂盒
2.NaHCO3,Ba(OH)3,H2SO4
3.HCL,NaAlO2,NaHSO4
4.Ca(OH)2,Na2CO3,BaCO3
谢谢了
要原因
bhclna2so4nano3na2co3
chclnaohna2co3nacl
dba(oh)2nahco3alcl3nahso4
C.MgCl2溶液和氨水D.盐酸和NaAlO2溶液
为什么
