BiologicalActivity
Nuclearfactor(erythroid-derived)-like2(Nrf2)pathwayactivator;inducesupregulationofantioxidantgeneexpression.Displayscytoprotectiveeffectsinhumanspinalcordastrocytes,oligodendrocyteprecursorcellsandhippocampalneuronsfollowinghydrogenperoxidechallenge.Exertsneuroprotectiveeffectsinvivoinexperimentalautoimmuneencephalomyelitis.Primarymetabolite(MMF,Cat.No.4511)available.
TechnicalData
| M.Wt | 144.13 |
| Formula | C6H8O4 |
| Storage | StoreatRT |
| Purity | ≥99% |
| CASNumber | 624-49-7 |
| PubChemID | 637568 |
| InChIKey | LDCRTTXIJACKKU-ONEGZZNKSA-N |
| Smiles | O=C(/C=C/C(OC)=O)OC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 14.41 | 100 | |
| ethanol | 7.21 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight144.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 6.94mL | 34.69mL | 69.38mL |
| 5mM | 1.39mL | 6.94mL | 13.88mL |
| 10mM | 0.69mL | 3.47mL | 6.94mL |
| 50mM | 0.14mL | 0.69mL | 1.39mL |
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