Tocris型号参数规格 Tocris BioscienceX中国代理价格，厂家,Tocris/Docetaxel/4056/10/10 mg,其他试剂,其他,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Docetaxel/4056/10/10 mg

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Tocris

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4056/10

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4000-520-616

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Description:MicrotubulestABIlizer

ChemicalName:[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylesterbenzenepropanoicacid

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Bindsandstabilizesmicrotubules;leadstocellcyclearrestandapoptosis.Displayssignificantantitumoractivityinovarianandgastrictumors.PreventsmicrotubuledepolymerizationanddisassemblyintheabsenceofGTP.Exhibitscytotoxicactivity.

TechnicalData

M.Wt	807.88
Formula	C₄₃H₅₃NO₁₄
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	114977-28-5
PubChemID	148124
InChIKey	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Smiles	O[C@@H]1C4=C(C)[C@@H](OC([C@H](O)[C@H]([C@]5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C[C@@](C(C)4C)(O)[C@@H](OC(C6=CC=CC=C6)=O)[C@@]([C@@]3(OC(C)=O)[C@H](OC3)C[C@@H]2O)([H])[C@]2(C)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	80.79	100
	ethanol	80.79	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight807.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.24mL	6.19mL	12.38mL
5mM	0.25mL	1.24mL	2.48mL
10mM	0.12mL	0.62mL	1.24mL
50mM	0.02mL	0.12mL	0.25mL

ProductDatasheets

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