Tocris报价单 Tocris配体,Tocris/GR 144053 trihydrochloride/1263/50/50 mg,其他试剂,其他,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/GR 144053 trihydrochloride/1263/50/50 mg

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Tocris/GR 144053 trihydrochloride/1263/50/50 mg

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Tocris

货号 /

1263/50

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4000-520-616

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Description:GlycoproteinIIb/IIIa(integrinα_IIbβ₃)receptorantagoNIST.Antithrombotic

ChemicalName:4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineaceticacidtrihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ApotentandselectiveplateletfibrinogenreceptorglycoproteinIIb/IIIa(GpIIb/IIIa)antagonist(IC₅₀=37nM).Orallyactiveandhighlyeffectiveatinhibitingthrombusformationinvivo.

TechnicalData

M.Wt	454.83
Formula	C₁₈H₂₇N₅O₂.3HCl
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	1215333-48-4
PubChemID	107895
InChIKey	GFZHNFOGCMEYTA-UHFFFAOYSA-N
Smiles	Cl.Cl.Cl.NC(=N)C1=CC=C(C=C1)N1CCN(CC1)C1CCN(CC(O)=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	45.48	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight454.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.2mL	10.99mL	21.99mL
5mM	0.44mL	2.2mL	4.4mL
10mM	0.22mL	1.1mL	2.2mL
50mM	0.04mL	0.22mL	0.44mL

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BiologicalActivity

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