EBVDextramerPackage1-PE
ProductCode:RX05-PE
Packageof4carefullyselectedEBVspecificMHCIDextramers(+1control),forsensitiveandspecificdetectionofantigen-specificTcellsusingflowcytometry.EachmulitmerisPElabeled.
Amount:5x50tests
Application(s):Cellularimmuneresponse,Immunemonitoring,T-cellassays
Indication(s)/Topic(s):Infection,Cancer,Hodgkin"slymphoma,Burkitt"slymphoma,Nasopharyngealcarcinoma,Dermatomyositis,Systemiclupuserythematosus,Rheumatoidarthritis,Sjgren"ssyndrome,Multiplesclerosis
DeliveryTime:10-12days
MHCIDextramerCollections
MHCIDextramerscombineadextranpolymerbackbonewithahighnumberofMHCandFluorochromemoleculesprovidingmulitplebindingdomainsforantigen-specificTcellreceptorbinding.Thisenhancestheirstainingintensityandincreasesresolutionaswellassignal-to-noiseratiowithminimalbackgroundstaining.Inaddition,thedextranbackbonestABIlizestheMHC-peptidecomplexesandfluorochromes.TheEBVsetisusefulforenumerationofEBV-specificCD8+Tcells,e.g.forimmunemonitoringinimmune-compromisedindividualsfollowingtransplantation,testingofvirus-specificvaccinesorprofilingofvirus-specificTcellresponses.TheDextramersareprovidedasPEconjugates.
Thefollowing5DextramersareprovidedwithPElabel
Dextramer:HLA-A*0201/GLCTLVAML-Antigen:BMLF-1
Dextramer:HLA-B*3501/HPVGEADYFEY-Antigen:EBNA-1
Dextramer:HLA-B*0702/RPPIFIRRL-Antigen:EBNA-3A
Dextramer:HLA-B*0801/FLRGRAYGL-Antigen:EBNA-3A
Dextramer:General/NegativeControl
BenefitsofMHCIDextramers®
-MoreMHCmoleculesandmorefluorochromesthanconventionalMHCmultimers
-Highersensitivity(importantforlow-affinityepitopesascommonlyfoundincancer&autoimmunedisease)
-Highstability
-Custom-madeDextramersavailableuponrequest
EBVDextramerPackage1-PE
SelectedReferencesforMHCIDextramers®
"CombinationImmunotherapyafterASCTforMultipleMyelomaUsingMAGE-A3/Poly-ICLCImmunizationsFollowedbyAdoptiveTransferofVaccine-PrimedandCostimulatedAutologousTCells"
Rapoportetal.,ClinCancerRes(2014)-PMID:24520093
"MolecularImprintofExposuretoNaturallyOccurringGeneticVariantsofHumanCytomegalovirusontheTcellRepertoire"
Smithetal.,SciRep(2014)-PMID:24509977
"ProbingtheeffectorandsuppressivefunctionsofhumanTcellsubsetsusingantigen-specificengineeredTcellreceptors"
Wanetal.,PLoSOne(2013)Fulltext
"HumanNaturalKillerCellsPreventInfectiousMononucleosisFeaturesbyTargetingLyticEpstein-BarrVirusInfection"
Chijiokeetal.,CellRep(2013)-PMID:24360958
EBVDextramerPackage1-PE
| Application | Immunemonitoring Immunohistochemistry T-cellassays |
| ProteinName | Selectedproteins |
| Organism | Epstein-Barrvirus(HHV-4) |
| Indication/Topic | Autoimmunedisease Burkitt"slymphoma Hodgkin"slymphoma Nasopharyngealcarcinoma |
FurtherInformation:
| Amount | 5x50tests |
| Specifications | SetofantigenspecificMHCclassImultimerswithdextranbackbone |
| Documentation | ProtocolandDatasheet |
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bhclna2so4nano3na2co3
chclnaohna2co3nacl
dba(oh)2nahco3alcl3nahso4
2.NaNO3FeCl3AgNO3
分别有什么现象？谢谢回答！
D,K2SO4Na2CO3BaCL2NaNO3
通过解答，教会我，谢谢
