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Tocris/LDV FITC/4577/1/1 mg
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Tocris/LDV FITC/4577/1/1 mg
品牌 / 
Tocris
货号 / 
4577/1
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Description:Fluorescentligandforα4β1(VLA-4)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Fluorescentligandthatbindstotheα4β1integrin(VLA-4)withhighaffinity(Kdvaluesare0.3nMand12nMforbindingtoU937cellsinthepresenceandabsenceofMn2+respectively).UsedtodetectVLA-4affinityandconformationalchanges.

TechnicalData

M.Wt1368.54
FormulaC69H81N11O17S
SequenceLDVPAAK(Modifications:Leu-1N-2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl-,Lys-6N-FITCconjugate)
StorageStoreat-20°C
CASNumber1207610-07-8
PubChemID91826076
InChIKeyPAAUNHNWVWSJKI-CBRXRBRLSA-N
SmilesCC(C)C[C@H](NC(=O)Cc1ccc(NC(=O)Nc2ccccc2C)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc(C(O)=O)c(c1)-c1c-2ccc(=O)cc-2oc2cc(O)ccc12)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinPBS(pH7.4)

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1368.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.73mL3.65mL7.31mL
5mM0.15mL0.73mL1.46mL
10mM0.07mL0.37mL0.73mL
50mM0.01mL0.07mL0.15mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet