BiologicalActivity
Myelinoligodendrocyteglycoprotein(MOG)35-55isaminorcomponentofCNSmyelin.Producesarelapsing-remittingneurologicaldiseasewithextensiveplaque-likedemyelination,commontothemanifestationsofmultiplesclerosis.InducesstrongTandBcellresponsesandishighlyencephalitogenic.
TechnicalData
| M.Wt | 2581.97 |
| Formula | C118H177N35O29S |
| Sequence | MEVGWYRSPFSRVVHLYRNGK |
| Storage | Desiccateat-20°C |
| CASNumber | 149635-73-4 |
| PubChemID | 24868190 |
| InChIKey | JMTCEFUSRHYJBF-DDJPMISGSA-N |
| Smiles | [H]N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto0.50mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight2581.97.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.39mL | 1.94mL | 3.87mL |
| 5mM | 0.08mL | 0.39mL | 0.77mL |
| 10mM | 0.04mL | 0.19mL | 0.39mL |
| 50mM | 0.01mL | 0.04mL | 0.08mL |
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