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Description:StimulatesBcl-XLmRNAtranscription;antiapoptotic
ChemicalName:(2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-Heptahydroxycholest-7-en-6-one
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Ecdysoneanalogthatactsasaninducerofecdysone-inducIBLegeneexpressionsystemsinmammaliancellsandtransgenicanimals.StimulatesBcl-XLmRNAtranscriptionandinhibitsTRAIL-andhFasL-inducedapoptosisinRKOcells.
TechnicalData
M.Wt | 496.63 |
Formula | C27H44O8 |
Storage | Storeat-20°C |
Purity | ≥97%(HPLC) |
CASNumber | 38778-30-2 |
PubChemID | 122217 |
InChIKey | LRJUYAVTHIEHAI-LHBNDURVSA-N |
Smiles | O[C@@H]1[C@H](O)C[C@](C(C=C3[C@@]([H])2[C@H](O)C[C@@]4(C)[C@](O)3CC[C@@]([H])4[C@](O)(C)[C@H](O)CCC(C)C)=O)(O)[C@]2(C)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | SolubleinDMSO |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight496.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.01mL | 10.07mL | 20.14mL |
5mM | 0.4mL | 2.01mL | 4.03mL |
10mM | 0.2mL | 1.01mL | 2.01mL |
50mM | 0.04mL | 0.2mL | 0.4mL |
MolarityCalculator
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Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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