BiologicalActivity
Methyl-lysine(Kme)readerdomaininhibitor;bindstotheMBTdomainoftheL3MBTL1protein(Kd=3.9μM).SelectivelyinhibitstheL3MBTL13XMBT-H4K20me1interactioninapeptidepulldownassay.
CompoundLibraries
UNC926hydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 373.72 |
| Formula | C16H21BrN2O.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 1184136-10-4 |
| PubChemID | 90488947 |
| InChIKey | DPPMBBHOXQOMJI-UHFFFAOYSA-N |
| Smiles | BrC1=CC=CC(C(N2CCC(N3CCCC3)CC2)=O)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.37 | 100 | |
| ethanol | 37.37 | 100 | |
| water | 37.37 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight373.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.68mL | 13.38mL | 26.76mL |
| 5mM | 0.54mL | 2.68mL | 5.35mL |
| 10mM | 0.27mL | 1.34mL | 2.68mL |
| 50mM | 0.05mL | 0.27mL | 0.54mL |
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