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Tocris/A 286982/4228/10/10 mg
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Tocris/A 286982/4228/10/10 mg
品牌 / 
Tocris
货号 / 
4228/10
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4000-520-616
Description:PotentinhibitoroftheLFA-1/ICAM-1interaction
ChemicalName:(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitoroftheLFA-1/ICAM-1interaction(IC50valuesare44and35nMinLFA-1/ICAM-1bindingandLFA-1-mediatedcelladhesionassaysrespectively).

TechnicalData

M.Wt453.55
FormulaC24H27N3O4S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber280749-17-9
PubChemID9846729
InChIKeyHTGGAYLWTDOFDK-PKNBQFBNSA-N
SmilesO=C(C)N1CCN(C(/C=C/C2=CC([N+]([O-])=O)=C(SC3=CC=CC=C3C(C)C)C=C2)=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.35100
ethanol22.6850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight453.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.2mL11.02mL22.05mL
5mM0.44mL2.2mL4.41mL
10mM0.22mL1.1mL2.2mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet