| Serum-SalivaCorrelation | NA |
| Sensitivity | 2.5μg/mL |
| SampleTestVolume | 25μL |
| RecommendedCollectionVolume | 50μL* |
| SpecialConsiderations | SIgAis LocationDependent SIgAis FlowRateDependent (μg/mL) PassiveDrool isaPreferredCollectionMethod |
| CollectionProtocol | DownloadPDF |
SecretoryImmunoglobulinA(SIgA)isasubclassofImmunoglobulinA(IgA),an antibody thatplaysacriticalroleinmucosalimmunity. SIgAisthemainimmunoglobulinfoundinmucoussecretionsfromthetearglands,salivaryglands,mammaryglands,therespiratorysystem,thegenito-urinarytract,andthegastrointestinaltract.(1)SIgAisnotsynthesizedbymucosalepithelialcellsinthesestructuresorderivedfromblood. Instead,itisproducedbyB-lymphocytesadjacenttothemucosalcells,thentransportedthroughthecellinteriors,andreleasedintothesecretionsfromthecells.(2)SIgAplaysakeyroleinprotectingvulnerableareassuchastheoralcavity,lungs,andgutfrominvADIngpathogens.(1) DifferencesinSIgAlevelsinthesalivafromdifferentglandshavebeenobservedinhumans,withthehighestlevelsfoundintheminorsalivaglands.(2,3) SIgAexhibitsadiurnalrhythm,decreasingfromthehighestlevelsinthemorningtothelowestintheevening.(4)
LevelsofSIgAinsalivavaryinresponsetophysicalandpsychologicalstressthroughinteractionswiththeautonomicnervoussystem.(5,6) SIgAlevelsinsalivaareaffectedbyflowrates,withconcentrationsnormallydecreasingasflowratesincrease. MeasurementofflowratesisadvisableinordertoexpressSIgAsecretionasafunctionoftime.(6)
- Holmgren,J.,Czerkinsky,C.(2005). Mucosalimmunityandvaccines. NatureMedicine,11(4Suppl),s45-53.
- Brandtzaeg,P.(2007).Dosalivaryantibodiesreliablyreflectbothmucosalandsystemicimmunity?AnnNYAcadSci,1098,288-311.
- Crawford,J.M.,TauBMAn,M.A.,SmithD.J.(1975). MinorsalivaryglandsasamajorsourceofsecretoryimmunoglobulinAinthehumanoralcavity. Science,190(4220),1206-9.
- Li,T.-L.,Gleeson,M.(2004).Theeffectofsingleandrepeatedboutsofprolongedcyclingandcircadianvariationonsalivaflowrate,immunoglobulinAandalpha-amylaseresponses. JSportsSci,22(11-12),1015-1024.
- Tsujita,S.,Morimoto,K.(1999). SecretoryIgAinsalivacanbeausefulstressMarker.EnvHealthPrevMed,4,1-8.
- Bishop,N.C.,Gleeson,M.(2009). Acuteandchroniceffectsofexerciseonmarkersofmucosalimmunity.FrontBiosci,1(14),4444-56.
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请问有什么方法检测细胞内活性氧更好,各位有什么经验,及相关试剂盒推荐一下。
C.MgCl2溶液和氨水D.盐酸和NaAlO2溶液
为什么
2.NaNO3FeCl3AgNO3
分别有什么现象?谢谢回答!
刚入这行,谢谢大家
A.H2SO4Na2SO4AgNO3BaCl2.
B.NaOHNa2CO3NaHSO4MgCl2
C.CaCl2NaNO3MgSO4BaCl2
D.HNO3KOHKClK2CO3

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