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Description:GPR119receptoragoNIST
ChemicalName:2-[[2-(4-Bromophenyl)-6-methyl-4-pyrimidinyl]amino]ethanol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
GPR119receptoragonist(EC50=2.5μMinHEK293cellsexpressinghumanGPR119).Enhancesinsulinsecretionstimulatedbyglucoseinvivo.Stimulatesproglucagongenepromoteractvity.Orallyavailable.
CompoundLibraries
AS1269574isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 308.17 |
| Formula | C13H14BrN3O |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 330981-72-1 |
| PubChemID | 5332859 |
| InChIKey | DUKPGOOUJNUIOI-UHFFFAOYSA-N |
| Smiles | BrC(C=C2)=CC=C2C1=NC(NCCO)=CC(C)=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 30.82 | 100 | |
| ethanol | 30.82 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight308.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.24mL | 16.22mL | 32.45mL |
| 5mM | 0.65mL | 3.24mL | 6.49mL |
| 10mM | 0.32mL | 1.62mL | 3.24mL |
| 50mM | 0.06mL | 0.32mL | 0.65mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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