Tocris代理，产品目录 Tocris Bioscience现货代理,Tocris/BRD 7552/5230/10/10 mg,转录表达,克隆和表达,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/BRD 7552/5230/10/10 mg

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Tocris

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5230/10

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Description:PDX1transcriptionfactorinducer;increasesinsulinexpression

ChemicalName:Methyl[2,3-O-bis(Benzo[1,3]dioxol-5-yl-carbamoyl)]-4-O-(4-ethoxycarbonyl-phenylcarbamoyl)-α-D-glucopyranoside

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PDX1transcriptionfactorinducer;upregulatesPDX1expressioninbothprimaryhumanisletsandductalcells.InducesepigeneticchangesinthePDX1promoterconsistentwithtranscriptionalactivation.IncreasesinsulinexpressioninPANC-1cells,primaryhumanisletsandhumanduct-derivedcells.

TechnicalData

M.Wt	711.63
Formula	C₃₃H₃₃N₃O₁₅
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1137359-47-7
PubChemID	23891512
InChIKey	AAOLIMLEFKWKOY-IXMSMLDRSA-N
Smiles	OC[C@@H]1[C@@H](OC(NC6=CC=C(C(OCC)=O)C=C6)=O)[C@H](OC(NC4=CC=C(OCO5)C5=C4)=O)[C@@H](OC(NC2=CC(OCO3)=C3C=C2)=O)[C@@H](OC)O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	71.16	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight711.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.41mL	7.03mL	14.05mL
5mM	0.28mL	1.41mL	2.81mL
10mM	0.14mL	0.7mL	1.41mL
50mM	0.03mL	0.14mL	0.28mL

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CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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PreparingStockSolutions

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