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Description:Krüppel-likefactor5(KLF5)inhibitor
ChemicalName:2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl(E)-3-(3-nitrophenyl)prop-2-enoate
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
InhibitorofKrüppel-likefactor5(KLF5)transcriptionfactor(IC50=2.3μM).Selectivelyactiveagainstcoloncancercellsinapanelof60differentcancercelllines.
TechnicalData
| M.Wt | 382.39 |
| Formula | C16H18N2O7S |
| Storage | Storeat+4°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 749872-43-3 |
| PubChemID | 5951923 |
| InChIKey | URVRJYLSUVXWBC-AATRIKPKSA-N |
| Smiles | O=C(OCC(N(C)C2CS(CC2)(=O)=O)=O)/C=C/C1=CC([N+]([O-])=O)=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 38.24 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight382.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.62mL | 13.08mL | 26.15mL |
| 5mM | 0.52mL | 2.62mL | 5.23mL |
| 10mM | 0.26mL | 1.31mL | 2.62mL |
| 50mM | 0.05mL | 0.26mL | 0.52mL |
MolarityCalculator
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Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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