Tocris产品目录价格 Tocris多肽,Tocris/Fatostatin A/4444/10/10 mg,转录表达,克隆和表达,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Fatostatin A/4444/10/10 mg

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Tocris

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4444/10

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4000-520-616

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Description:CellpermeableinhibitorofSREBPactivation

ChemicalName:4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridinehydrobromide

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofsterolregulatoryelementbindingprotein(SREBP);impairstheactivationofSREBP-1andSREBP-2.ExhibitsantiproliferativeeffectsinDU145cellsindependentlyofIGF-1signaling(IC₅₀=0.1μM);reverseshyperglycemiaindiabetic(ob/ob)mice.Cellpermeable.

TechnicalData

M.Wt	375.33
Formula	C₁₈H₁₈N₂S.HBr
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	298197-04-3
PubChemID	2850562
InChIKey	RJCFNQZVFUMORB-UHFFFAOYSA-N
Smiles	CCCC1=CC(C2=NC(C3=CC=C(C)C=C3)=CS2)=CC=N1.Br

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	7.51	20
	ethanol	3.75	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight375.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.66mL	13.32mL	26.64mL
5mM	0.53mL	2.66mL	5.33mL
10mM	0.27mL	1.33mL	2.66mL
50mM	0.05mL	0.27mL	0.53mL

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SolubilityData

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