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Description:Highlypotentandselective5-HTuptakeinhibitor
ChemicalName:1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrilehydrobromide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Highlyselectiveandpotent5-HTuptakeinhibitorwithnoeffectonnoradrenalinordopamineuptake(IC50valuesare1.8,8800and41000nMrespectively).HasnegligIBLeactivityatawiderangeofreceptors.
TechnicalData
M.Wt | 405.31 |
Formula | C20H21FN2O.HBr |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 59729-32-7 |
PubChemID | 77995 |
InChIKey | WIHMBLDNRMIGDW-UHFFFAOYSA-N |
Smiles | Br.CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto50mMinethanolandto10mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight405.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.47mL | 12.34mL | 24.67mL |
5mM | 0.49mL | 2.47mL | 4.93mL |
10mM | 0.25mL | 1.23mL | 2.47mL |
50mM | 0.05mL | 0.25mL | 0.49mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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