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Description:PotentinhibitorofL-glutamateuptakeintosynapticvesicles
ChemicalName:6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino-5-hydroxy-1,3-naphthalenedisulphonicacid]tetrasodiumsalt
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentinhibitorofL-glutamateuptakeintosynapticvesicles.AlsoinhibitsAMPAandkainatereceptor-mediatedcurrents(IC50valuesare220and150nMrespectively).P2X-selectivepurinoceptorantagoNIST.
TechnicalData
M.Wt | 960.82 |
Formula | C34H24N6Na4O14S4 |
Storage | StoreatRT |
Purity | ≥95%(HPLC) |
CASNumber | 314-13-6 |
PubChemID | 101102794 |
InChIKey | ATNOAWAQFYGAOY-UHFFFAOYSA-J |
Smiles | [Na+].[Na+].[Na+].[Na+].CC1=CC(=CC=C1N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S([O-])(=O)=O)S([O-])(=O)=O)C1=CC(C)=C(C=C1)N=NC1=C(O)C2=C(N)C(=CC(=C2C=C1)S([O-])(=O)=O)S([O-])(=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 9.61 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight960.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.04mL | 5.2mL | 10.41mL |
5mM | 0.21mL | 1.04mL | 2.08mL |
10mM | 0.1mL | 0.52mL | 1.04mL |
50mM | 0.02mL | 0.1mL | 0.21mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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