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Tocris/GBR 12935 dihydrochloride/0514/50/50 mg

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Tocris/GBR 12935 dihydrochloride/0514/50/50 mg

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Tocris

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0514/50

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4000-520-616

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Description:Selectivedopamineuptakeinhibitor

ChemicalName:1-(2-Diphenylmethoxyethyl)-4-(3-phenylpropyl)piperazinedihydrochloride

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveinhibitorofdopamineuptake(K_D=5.5nMinratstriatalmembranes).

TechnicalData

M.Wt	487.51
Formula	C₂₈H₃₄N₂O.2HCl
Storage	Desiccateat-20°C
CASNumber	67469-81-2
PubChemID	11957553
InChIKey	NQWRSILGEXNJIT-UHFFFAOYSA-N
Smiles	Cl.Cl.C(CN1CCN(CCOC(C2=CC=CC=C2)C2=CC=CC=C2)CC1)CC1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	2.44	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight487.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.05mL	10.26mL	20.51mL
5mM	0.41mL	2.05mL	4.1mL
10mM	0.21mL	1.03mL	2.05mL
50mM	0.04mL	0.21mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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