BiologicalActivity
Inhibitsstriataldopamineuptakeandhippocampal5-HTuptakeinsynaptosomes(IC50valuesare467and558nMrespectively).AdmiNISTrationcausesadecreaseindopamineand5-HTtransporterfunction.SyntheticCNSstimulant;brainpenetrant.
TechnicalData
| M.Wt | 213.7 |
| Formula | C11H15NO.HCl |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 1189726-22-4 |
| PubChemID | 46782120 |
| InChIKey | DLQZFTUKJGRPLZ-UHFFFAOYSA-N |
| Smiles | CC1=CC=C(C(C(C)NC)=O)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 21.37 | 100 | |
| ethanol | 10.69 | 50 | |
| water | 21.37 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight213.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.68mL | 23.4mL | 46.79mL |
| 5mM | 0.94mL | 4.68mL | 9.36mL |
| 10mM | 0.47mL | 2.34mL | 4.68mL |
| 50mM | 0.09mL | 0.47mL | 0.94mL |
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